I found it strange at first that there are two versions around (cosmetically at least).
I bet the later version (which I have) is compatible with the DS Lite, as to not having to butcher the cart itself to fit in.
Tbh, I've never seen the 3in1+ around, the only difference seems to be double the NOR RAM, taht's all.
Regarding the actual Opera ROM:
The original would not boot at all (verified), because it needs the original cart (read that somewhere).
Then tried a patched one: boots.
Then found another intro hacked version: boots, but similar problem.
Got another one: dunno what version, but similar problem.